Research Impact

Dr. Lugogo stresses that good asthma control is an achievable goal. “If you have asthma, don’t just let it rule your life. Many patients adjust their activities around their breathing doing less and less. You CAN enjoy a better quality of life!”

KALOS, LOGOS: Triple therapy inhaler improves lung function in asthma

Healio News | CHEST Annual Meeting - November 07, 2025

“This reinforces the positive impact of triple therapy on patients with asthma uncontrolled on inhaled corticosteroids/long-acting beta agonists and provides us with further evidence that this treatment should be used in this patient population,” Njira L. Lugogo, MD, associate professor of internal medicine and director of the division of pulmonary and critical care medicine’s asthma program at Michigan Medicine, told Healio.

"In addition, this can be implemented in primary care where a large proportion of poorly controlled patients seek care. It is also important to note that the high dose triple combination therapy has a medium dose ICS which is important as we embrace ICS stewardship and avoid long term use of high dose ICS. In addition, unlike COPD the asthma triple includes a higher dose of glycopyrrolate due to the higher lung function that was achieved on this dose."

Summary:

After 24 weeks using the Breztri Aerosphere inhaler, people could blow out 71 milliliters more air (on average) in one second, in the morning before taking their medicine, compared to before they started.
This shows the inhaler really works, not just for a short time, but it helps your lungs stay better for many weeks.

Rethinking Mild Asthma in Primary Care: Real-World Lessons on As-Needed ICS-SABA Use

American Medical Journal · July 31, 2025

BATURA trial results showed that as-needed use of an ICS-SABA combination may help control symptoms and mitigate exacerbation risk in often overlooked patients with mild asthma.

"What treatments are available for severe asthma?"

Michigan Medicine YouTube · May 31, 2023Dr. Njira Lugogo, MD talks about what treatments are available for severe asthma.

Video Link (YouTube)

So you've got severe asthma but severe asthma doesn't have to have you.

"Asthma is Tricky!"

Michigan Medicine YouTube · April 14, 2022Listen to Michigan Medicine patient, Latasha Phelan-Wright discuss her journey to relief. This short video is from an in-depth discussion with specialists from two inter-connected disciplines, Dr. Njira Lugogo, MI Asthma Research Director and Dr. Anna Kovalszki, Professor, Allergy and Immunology Division.

Moderator Ed Bottomley - Michigan Medicine Communications

Watch Full Session Here! (YouTube)

Dedicated Michigan Medicine specialists help solve vexing care issues through research and collaboration!

When all else failed, biologics helped her breathe again

University of Michigan Health Blog · December 6, 2021

Diagnosed with asthma at age 23. It took her more than 30

years to finally get it under control with biologics.

Author Jane Racey Gleeson - December 06, 2021 12:07 PM

Improved treatment would not have been possible without alternatives found through prior research!

Publications

If you are interested in reading more, click here for a sample of Dr. Lugogo's publications.

For Referring Providers:

Why Refer Patients to
Severe Asthma Research Study?

Having treated thousands of patients who struggle with severe asthma throughout her career, Dr. Njira Lugogo is committed to continuous treatment improvement based on advances found through research. New treatment options are becoming available as researchers learn more. Do you have a patient you can refer to one of our severe asthma research studies in progress.

Joining one of our study trials may help one of your patients and advance care. Your referrals are important!

For Prospective Participants

Interested in Joining a
Severe Asthma Research Study?

We are building a database of patients who are interested in being considered for our severe asthma research studies. Patients can add themselves to the database by completing a short screening survey. If we have a study for which you are a good fit, we will reach out for further review. Be your own advocate for continued progress!

Learn more about Severe Asthma Research studies we are currently recruiting for. Helping us may help YOU!

Get Involved!
miasthmaresearch@med.umich.edu

(734) 764-5530